Bacterial link to colon cancer studied

OKLAHOMA CITY (UPI) — U.S. researchers say they have discovered the human colon reacts to changes in a common bacterium in ways that might promote the growth of cancer.

Researchers from the Department of Veterans Affairs Medical Center in Oklahoma City and from the University of Oklahoma studied a bacterium called Enterococcus faecalis that’s commonly found in the human colon. The scientists said that bacterium can release a type of oxygen molecule called a superoxide, that damages DNA and might promote the growth of cancer cells in the colon.

“We wanted to investigate how colon cells respond to normal gut bacteria that can damage DNA, like E. faecalis,” said Professor Mark Huycke of the VA Medical Center. He added that the researchers “found superoxide from E. faecalis led to strong signaling in immune cells called macrophages. It also altered the way some cells in the gut grew and divided and even increased the productivity of genes that are associated with cancer.”

Huycke said the findings are among the first to explore mechanisms by which normal gut bacteria damage DNA and alter gene regulation in the colon that might lead to cancer.

The study appears in the Journal of Medical Microbiology.


Copyright 2008 by United Press International
arcamax.com

 
 

Leave a Reply

 

Resources

Hi dear friends and visitors!! thanks for visiting me here!! Have a great and blessed day!!




WANT TO EXCHANGE LINK WITH ME? READ HERE FIRST

Extras

All photographs used on this site, including thumbnails, are the Author's property and are ©copyright. Please do not use our photos without our permission. If you wish to use one of our photos on your personal website or blog, please send us the link to the page where it is being used and the photo must be linked back to this site. We hope that you respect the Authors' request. Thank you for your respect and understanding!

Copyright © 2013 Health, Food and Travel | All Rights Reserved

Blog Design by Simple Blog MakeOver